GC-MS analysis of methanolic extract of stem and root bark of Kirganelia reticulata for bioactive components

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Year 2017 Vol 6 Issue 2
Document Type : ORIGINAL ARTICLE
¹R. A. Reddy1, ²V. Krishna1, ³S. Usha2, ⁴R. Bharathi3, ⁵V. K. Murthy4
¹1Department of P.G. Studies & Research in Biotechnology & Bioinformatics, Kuvempu University, Shankaraghatta- 577451, Karnataka, India;
²1Department of P.G. Studies & Research in Biotechnology & Bioinformatics, Kuvempu University, Shankaraghatta- 577451, Karnataka, India;
³2 Department of Biotechnology, Dayananda Sagar College of Biological Sciences, Bangalore 560078, Karnataka, India;
⁴3Department of Computer Science Engineering, BMS Institute of Technology, Bangalore-560 064; Karnataka, India;
⁵4Department of Biotechnology, PES University, Bangalore-560 085, Karnataka; India
Abstract

To identify the bioactive components present in the stem and root bark extracts of Kirganelia reticulata
The Soxhlet extracted crude methanolic extracts of stem and root bark of Kirganelia reticulata were analysed by GC-MS.
Results: GC-MS analysis revealed the presence of 27 and 24 potential bioactive components in stem and root bark extract of Kirganelia reticulata respectively. These components were mostly esters, phenols, flavonoids, aldehydes, alkaloids, sterols and terpenoids with biological activity. Conclusion: Many of the bioactive components identified in the study are multifunctional in nature with potent antioxidant, antimicrobial, antifungal, antiviral, candidicide, hypocholesterolemic, anti-inflammatory, anti-cancer, anti-androgenic, antiasthma, diuretic and hepatoprotective in nature justifying the use of this plant in traditional medicine for treating various ailments and also providing an opportunity for identification of potential drug candidates.
Keywords
Brinjal, poly phenols, ß-carotene, antioxidants, proteins
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